Trent Williams to miss time with high ankle sprain
Shanahan added that Williams could miss four-to-six weeks, but that won't be confirmed until his swelling decreases.
The veteran tackle suffered the injury after Broncos defensive lineman landed on his leg in the third quarter of the team's Sunday Night Football loss.
Colton McKivitz played the majority of the snaps at left tackle following Williams' exit, but Jaylon Moore briefly filled in initially. A fifth-round pick in 2020, McKivitz has started four games for the 49ers over his career.
A nine-time Pro Bowler, Williams has been a key cog on the 49ers' offensive line for the last three seasons. He's made 32 starts for the team and earned his first All-Pro nod in 2021.