Muzzin suffered a fractured foot on Dec. 27 and has missed the club's last 10 games. He's been a key defender for the Leafs this season, leading the team in hits and ranking second in blocks. He's also chipped in offensively with 13 points in 38 contests.
Moore hasn't seen action since Dec. 21 due to a concussion. The 24-year-old has managed three goals and five points in 22 games this season.
The pair suited up for the Marlies on Friday to get back to game speed, with Moore potting a goal in a 5-2 loss to the Cleveland Monsters.
The Maple Leafs will resume play after the All-Star break when they visit the Nashville Predators on Monday.