Week 5 betting primer: News and notes for the 13 remaining games

Odds and data via theScore Bet and ESPN Bet

Through four weeks of the NFL season, we have a large enough sample size that we don't need to rely on preseason assumptions to determine which side of the spread we like.

Most of our offseason questions have been answered. We have a good idea of which teams will be playoff contenders and which are already looking toward the draft.

With that in mind, let's look at the remaining games for the Week 5 slate, including the news and notes that may help you decide who to bet.

Sunday 9:30 a.m. ET (London game)

• Jets-Vikings is the first London game of the season.
• The undefeated Vikings are a perfect 4-0 ATS. The Jets are 2-2 ATS.
• This spread suggests the Vikings would be roughly 4.5-point favorites if the game were played in Minnesota.
• The Vikings are 3-0 in London, winning most recently in 2022.
• The Jets are 0-1 when traveling to the U.K., losing to the Falcons in 2021.
• Sam Darnold will face off against the team that drafted him third overall in 2018. His passing yards prop is 219.5, but the Jets have the NFL's second-best passing defense.
• Darnold is the fifth-leading favorite to win MVP, and Vikings head coach Kevin O'Connell is the favorite to win COY.

Sunday 1 p.m. ET slate

• The surprise NFC East-leading Commanders are 3-1 straight up and 3-1 ATS.
• The Browns are 1-3 both straight up and ATS.
• Washington has scored 80 points combined in its last two games. Its team total is set at 23.5 points. Cleveland has scored 66 points all season.
• Jayden Daniels is the odds-on favorite (-150) to win the Offensive Rookie of the Year award. His passing yards prop against the Browns is 212.5, which he's soared past the last three weeks.

• The Jaguars are the NFL's only winless team.
• Anthony Richardson and Jonathan Taylor are questionable for the game.
• Backup Joe Flacco came in for the Colts in Week 4, throwing for 168 yards on 16 completions and two touchdowns.
• This game features two of the league's worst defenses. The Colts are allowing the most yards per game (422.5) but are managing to keep points off the board (T14 in points allowed), while the Jaguars allow the third-most yards per game (391.0).

• This could be a preview of the AFC Championship Game. The Bills are the third-highest favorite to win the conference, while the Texans are the fourth.
• Despite their 3-1 record, the Texans are one of two teams yet to cover a spread this season.
• The Bills beat up on the Cardinals, Dolphins, and Jaguars to open their season before the Ravens annihilated them by 25 points on Sunday Night Football.
• Buffalo is 23-11 following a loss in the Josh Allen era, the second-best mark during that span behind the Chiefs.

• This AFC East matchup features the week's lowest total. These are the two lowest-scoring offenses in the league. Miami has posted 45 points in four games, while New England has only scored 52.
• The Dolphins are 0-4 ATS and. The Patriots are 1-2-1. Both teams are 1-3 straight up.
• Miami will continue to use Tyler "Snoop" Huntley as its starting quarterback, while the Patriots continue to leave rookie Drake Maye on the bench and start Jacoby Brissett.

• This spread opened with the Bears as 5.5-point favorites.
• The Panthers have scored 60 points since turning the keys over to Andy Dalton. His passing prop is 217.5 against Chicago. He's gone over that the past two games, but the Bears hold opponents to 174.5 passing yards per game.
• Chicago is 2-0 ATS at home, winning by an average margin of 6.5 points.
• Carolina's only cover came when the team was a 5.5-point underdog in Las Vegas.

• The Bengals secured their first win of the season with a 10-point victory over the Panthers in Week 4.
• The Ravens beat the Bills by 25 at home in Week 4.
• Baltimore is 2-2 ATS but has covered in its last two contests. Cincy is also 2-2 ATS, but both covers were on the road.
• This spread feels like an overreaction to the Bengals beating a bad Panthers team rather than the Ravens dismantling another AFC contender.

Sunday 4 p.m. ET slate

• Both the Cardinals and 49ers are 2-2 ATS this season.
• San Francisco returned to .500 with a 17-point victory at home over the Patriots. Despite several injuries to key offensive players, the 49ers are averaging the second-most yards per game and eighth-most points per contest.
• Arizona gave up 42 points to the Commanders. The Cardinals' defense has allowed the fourth-most points, resulting in this being the highest total of the slate.

• The game features the second-lowest total of the week. The Broncos have scored the fifth-fewest points and accumulated the sixth-fewest yards.
• Denver's Bo Nix threw for only 60 yards in the team's Week 4 upset of the Jets. His passing prop for Week 5 is 188.5 yards.
• The Broncos are 3-1 ATS while pairing one of the league's best defenses with one of the worst offenses.
• Off-field storylines are already swirling for the Raiders. Star wideout Davante Adams sat out last week with a hamstring injury and has requested a trade.
• Without him, Gardner Minshew threw for only 130 yards last week. His passing prop is 189.5 against the league's third-best passing defense.

• The Giants could be without rookie standout Malik Nabers as he works through concussion protocol.
• Seahawks quarterback Geno Smith leads the NFL in passing yards with 1,182 through four games. His passing total against New York is 250.5, which he surpassed the last three weeks.
• The Giants are 2-2 ATS, while the Seahawks are 1-2-1.
• Seattle is on a short week after playing Monday night, while the Giants have had extra rest following their loss to the Cowboys on Thursday night.

• Jordan Love returned for the Packers in Week 4, throwing for 389 yards and four touchdowns in a comeback effort against the Vikings.
• Green Bay went 2-0 in Love's absence, covering both games as underdogs. Love's passing total is 258.5.
• The Rams have the fourth-worst point differential in the league at -40, including their 31-point loss to the Cardinals. They're 1-3 straight up.
• Matthew Stafford will be without his two favorite weapons - Cooper Kupp and Puka Nacua - for a third straight game. Stafford's passing prop is 230.5. He's failed to reach that in his last three games.
• Since Sean McVay was hired in 2017, the Rams have the best record against the spread (25-17-4) following a loss.

Sunday Night Football

• Justin Fields' production and an elite defense have given Pittsburgh a 3-1 record straight up and ATS.
• The Cowboys failed to cover in Week 4 versus the Giants after Brandon Aubrey missed a late field goal.
• Dallas hasn't covered since its Week 1 win over the Browns.
• Pittsburgh allows 13.3 points per game, the league's second-fewest. The Cowboys' team total is 20.5, which they have gone over in two of their four games.

Monday Night Football

• Injuries continue to plague the Chiefs' offense with Rashee Rice's knee injury holding him out Monday night and likely much longer.
• Yet Kansas City is still 4-0 (3-1 ATS), relying heavily on a stout defense.
• The Saints have lost back-to-back weeks after scoring 91 points in their first two games.
• Travis Kelce had his best game of the season last week after Rice exited the game, catching seven passes for 89 yards. His receptions prop against New Orleans is 5.5 and his receiving prop is 56.5.