He was placed on the injured reserve Tuesday. The third-year pro reportedly won't require surgery.
Goedert suffered the injury in Week 3, exiting in the first half of the Eagles' 23-23 tie with the Cincinnati Bengals.
In three appearances this season, the South Dakota State product has notched 13 receptions for a team-high 138 yards and one touchdown.
The Eagles will take their 0-2-1 record into a Week 4 tilt against the San Francisco 49ers.