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Wager: Eagles over 23.5 points
Credit Drew Brees and the offense for bailing out the Saints' defense so far this season. An 8-1 team with the top scoring offense in the league is actually negative in adjusted net yards per game thanks to a defense that is allowing 6.2 per contest, fourth worst in the NFL.
It should be a favorable matchup in the dome for the Eagles, who are posting 5.7 yards per play, but 5.9 when adjusting for strength of schedule. The Eagles have also been one of the best scoring teams away from home, hitting the team total in nine of the last 11 with Carson Wentz under center. Given the offense on the opposite sideline and its knack for quick scores, Philly should have plenty of opportunities.
Wager: Under 47
Pittsburgh-Jacksonville will feature one top-tier defense and another that's looked rather subpar over the last month-plus. Before the season, it'd be a no-brainer which defense is which, but it's the Steelers who have played at an elite level this year while the Jaguars have fallen off.
The Steelers now rank No. 2 in adjusted yards per play allowed at 5.1; the Jags are right behind that mark at 5.3 but have allowed more than 30 points per game over the last five. We expect Pittsburgh's underrated defense to continue fighting and Jacksonville's to get back on track to keep this one under the total.
Wager: Raiders +5.5
Betting on the Raiders is a tough pill to swallow, but it's even more difficult to lay five points with a Cardinals team that's posting 4.2 adjusted yards per play on offense behind a rookie quarterback, and is minus-1.0 in adjusted net yards this season.
Recommended Pick: Over 51.5
The word "struggle" has been used to describe Tampa Bay's offensive performance in its 16-3 loss to Washington in Week 10. But the Buccaneers didn't actually struggle. The offense racked up more than 500 yards but was hampered by four turnovers and zero points in five red-zone trips. Those problems are easier to fix than an offense that can't move the chains.
With Tampa chucking the ball all over the place and a defense that is allowing an absurd amount of points away from home, scoring should come easy in this one.
Recommended Pick: Over 46.5
The Chargers' defense hasn't been tested all that much as of late, getting the 49ers, Browns, Titans, and Raiders (twice) over the last six games. Denver has been able to move the ball at the same efficiency as offenses such as the Falcons and Eagles but has been plagued by red-zone woes and untimely turnovers. We already know the Chargers can put up points at a torrid pace, so we're thinking divisional shootout for Sunday afternoon.
Top plays: 19-8-2 (70.3 percent)
Overall record: 30-17-1 (63.8 percent)
Alex Kolodziej is theScore's betting writer. He's a graduate of Eastern Illinois who has been involved in the sports betting industry for 11 years. He can quote every line from "Rounders" and appreciates franchises that regularly wear alternate jerseys. Find him on Twitter @AlexKoIodziej.